East Perth is an inner suburb of Perth, Western Australia, located next to the Perth CBD. Claise Brook and Claisebrook Cove are within the suburb.

Primarily an industrial area in the early twentieth century, it was the location of the East Perth Gas Works, East Perth Power Station (which was decommissioned and the building is being renovated for other purposes), the East Perth railway yard, and engine sheds.

From the early 1980s, virtually all of the residential real estate on the western side of Lord Street became home to commercial enterprises; the buildings remain, either single or duplex dwellings previously inhabited mostly by migrant families.

East Perth is the location of Perth's significant early colonial era cemetery, which contains graves of many early colonial families. Its condition is marginal due to the loss of many headstones and lack of adequate record of graves, only 800 of the estimated 10,000 grave sites have been identified.

The former East Perth railway yard and engine sheds were removed in the 1960s and have been redeveloped into the Railway headquarters - consolidating a very scattered system of offices and sections for the railways.

East Perth serves as the main hub for country and interstate rail services and Road Coach services. Departing from the station are services such as the Prospector, Avonlink, tourist trains, and the most famous train in Australia, the Indian Pacific.

The original East Perth railway station is now called Claisebrook, and while it has the same number of platforms that it did in the 1960s, the original buildings have given way to modern shelters.

It is also the location of the Goongoongup Bridge on the railway to Bunbury for the South Western Railway.